Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders

Importance

Ipilimumab and other immune therapies are effective treatment options for patients with advanced melanoma but cause frequent immune-related toxic effects. Autoimmune diseases are common, and the safety and efficacy of ipilimumab therapy in patients with preexisting autoimmune disorders is not known.

Objective

To determine the safety and efficacy of ipilimumab therapy in patients with advanced melanoma with...