How many carbonic anhydrase inhibition mechanisms exist?
Volume: 31, Issue: 3, Pages: 345 - 360
Published: Nov 30, 2015
Abstract
Six genetic families of the enzyme carbonic anhydrase (CA, EC 4.2.1.1) were described to date. Inhibition of CAs has pharmacologic applications in the field of antiglaucoma, anticonvulsant, anticancer, and anti-infective agents. New classes of CA inhibitors (CAIs) were described in the last decade with enzyme inhibition mechanisms differing considerably from the classical inhibitors of the sulfonamide or anion type. Five different CA inhibition...
Paper Details
Title
How many carbonic anhydrase inhibition mechanisms exist?
Published Date
Nov 30, 2015
Volume
31
Issue
3
Pages
345 - 360
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