Current methods for the synthesis of homogeneous antibody–drug conjugates
Abstract
Development of efficient and safe cancer therapy is one of the major challenges of the modern medicine. Over the last few years antibody-drug conjugates (ADCs) have become a powerful tool in cancer treatment with two of them, Adcetris® (brentuximab vedotin) and Kadcyla® (ado-trastuzumab emtansine), having recently been approved by the Food and Drug Administration (FDA). Essentially, an ADC is a bioconjugate that comprises a monoclonal antibody...
Paper Details
Title
Current methods for the synthesis of homogeneous antibody–drug conjugates
Published Date
Nov 1, 2015
Journal
Volume
33
Issue
6
Pages
775 - 784
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Notes
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