Co-administration of ezetimibe and a statin in management of dyslipidemias: a meta-analysis of clinical trials

Introduction: Patients, who have above-target low-density lipoprotein cholesterol (LDL-C) levels, are at increased risk for developing coronary heart disease and cardiovascular disease. Statin monotherapy, which decreases the production of exogenous cholesterol, might not be enough to decrease LDL-C levels. Coadministration of a cholesterol absorption inhibitor with a statin may be more effective at decreasing serum LDL-C levels and improving...