Central Renin–Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II–Elicited Hypertension
Abstract
Obesity has been shown to promote renin-angiotensin system activity and inflammation in the brain and to be accompanied by increased sympathetic activity and blood pressure. Our previous studies demonstrated that administration of a subpressor dose of angiotensin (Ang) II sensitizes subsequent Ang II-elicited hypertension. The present study tested whether high-fat diet (HFD) feeding also sensitizes the Ang II-elicited hypertensive response and...
Paper Details
Title
Central Renin–Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II–Elicited Hypertension
Published Date
Jan 1, 2016
Journal
Volume
67
Issue
1
Pages
163 - 170
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