Somato-axodendritic release of oxytocin into the brain due to calcium amplification is essential for social memory
Volume: 66, Issue: 4, Pages: 275 - 282
Published: Nov 19, 2015
Abstract
Oxytocin (OT) is released into the brain from the cell soma, axons, and dendrites of neurosecretory cells in the hypothalamus. Locally released OT can activate OT receptors, form inositol-1,4,5-trisphosphate and elevate intracellular free calcium (Ca2+) concentrations [(Ca2+) i ] in self and neighboring neurons in the hypothalamus, resulting in further OT release: i.e., autocrine or paracrine systems of OT-induced OT release. CD38-dependent...
Paper Details
Title
Somato-axodendritic release of oxytocin into the brain due to calcium amplification is essential for social memory
Published Date
Nov 19, 2015
Volume
66
Issue
4
Pages
275 - 282
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