miR-301a promotes intestinal mucosal inflammation through induction of IL-17A and TNF-α in IBD
Abstract
Objective
MicroRNA (miR)-301a is known to be involved in the tumourigenesis and pathogenesis of several autoimmune diseases, but it remains unclear whether miR-301a is associated with the pathogenesis of IBD.Methods
miR-301a expression was assessed in peripheral blood mononuclear cells (PBMC) and inflamed mucosa of patients with IBD by quantitative real-time-PCR. Peripheral blood CD4+ T cells were transduced with...Paper Details
Title
miR-301a promotes intestinal mucosal inflammation through induction of IL-17A and TNF-α in IBD
Published Date
Sep 3, 2015
Journal
Volume
65
Issue
12
Pages
1938 - 1950
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Notes
History