Age-related differences in regional brain volumes: A comparison of optimized voxel-based morphometry to manual volumetry
Abstract
Regional manual volumetry is the gold standard of in vivo neuroanatomy, but is labor-intensive, can be imperfectly reliable, and allows for measuring limited number of regions. Voxel-based morphometry (VBM) has perfect repeatability and assesses local structure across the whole brain. However, its anatomic validity is unclear, and with its increasing popularity, a systematic comparison of VBM to manual volumetry is necessary. The few existing...
Paper Details
Title
Age-related differences in regional brain volumes: A comparison of optimized voxel-based morphometry to manual volumetry
Published Date
Oct 1, 2009
Journal
Volume
30
Issue
10
Pages
1657 - 1676
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