Possible involvement of T helper type 2 responses to Toll-like receptor ligands in IgG4-related sclerosing disease
Abstract
We report a case of immunoglobulin G4 (IgG4)-related sclerosing disease involving the pancreas, liver and salivary glands. Massive infiltration of IgG4-expressing plasma cells was seen in the liver and submandibular lymph nodes. Interestingly, accumulation of IgG4-expressing plasma cells was also seen in the colon and terminal ileum. Peripheral blood mononuclear cells (PBMCs) isolated from this patient exhibited enhanced production of IgG4 and...
Paper Details
Title
Possible involvement of T helper type 2 responses to Toll-like receptor ligands in IgG4-related sclerosing disease
Published Date
Mar 23, 2010
Journal
Volume
59
Issue
4
Pages
542 - 545
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