Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression

Background Hippocampal volume reduction has been reported inconsistently in people with major depression. Aims To evaluate the interrelationships between hippocampal volumes, memory and key clinical, vascular and genetic risk factors. Method Totals of 66 people with depression and 20 control participants underwent magnetic resonance imaging and clinical assessment. Measures of depression severity, psychomotor retardation, verbal and visual...