Garcinia cambogia (Hydroxycitric Acid) as a Potential Antiobesity Agent

Hydroxycitric acid, the active ingredient in the herbal compound Garcinia cambogia, competitively inhibits the extramitochondrial enzyme adenosine triphosphate-citrate (pro-3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans.To evaluate the efficacy of G cambogia for body weight and fat mass loss in overweight human...