Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4
Volume: 306, Issue: 3, Pages: F351 - F358
Published: Feb 1, 2014
Abstract
Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that acts on the proximal tubule to decrease phosphate reabsorption and serum levels of 1,25-dihydroxyvitamin D₃ [1,25(OH)₂ Vitamin D₃]. Abnormal FGF23 metabolism has been implicated in several debilitating hypophosphatemic and hyperphosphatemic disorders. The renal receptors responsible for the phosphaturic actions of FGF23 have not been elucidated. There are four fibroblast growth...
Paper Details
Title
Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4
Published Date
Feb 1, 2014
Volume
306
Issue
3
Pages
F351 - F358
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