Role of Akt Signaling in Vascular Homeostasis and Angiogenesis

Volume: 90, Issue: 12, Pages: 1243 - 1250
Published: Jun 28, 2002
Abstract
Akt is a serine/threonine protein kinase that is activated by a number of growth factors and cytokines in a phosphatidylinositol-3 kinase-dependent manner. Although antiapoptotic activity of Akt is well known, it also regulates other aspects of cellular functions, including migration, glucose metabolism, and protein synthesis. In this review, Akt signaling in endothelial cells and its critical roles in the regulation of vascular homeostasis and...
Paper Details
Title
Role of Akt Signaling in Vascular Homeostasis and Angiogenesis
Published Date
Jun 28, 2002
Volume
90
Issue
12
Pages
1243 - 1250
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