Dosimetric inter-institutional comparison in European radiotherapy centres: Results of IAEA supported treatment planning system audit.

Published on Apr 13, 2014in Acta Oncologica4.089
· DOI :10.3109/0284186X.2013.840742
Eduard Gershkevitsh6
Estimated H-index: 6
,
Csilla Pesznyak1
Estimated H-index: 1
+ 5 AuthorsJacob Van Dyk16
Estimated H-index: 16
(IAEA: International Atomic Energy Agency)
Sources
Abstract
AbstractBackground and purpose. One of the newer audit modalities operated by the International Atomic Energy Agency (IAEA) involves audits of treatment planning systems (TPS) in radiotherapy. The main focus of the audit is the dosimetry verification of the delivery of a radiation treatment plan for three-dimensional (3D) conformal radiotherapy using high energy photon beams. The audit has been carried out in eight European countries – Estonia, Hungary, Latvia, Lithuania, Serbia, Slovakia, Poland and Portugal. The corresponding results are presented. Material and methods. The TPS audit reviews the dosimetry, treatment planning and radiotherapy delivery processes using the ‘end-to-end’ approach, i.e. following the pathway similar to that of the patient, through imaging, treatment planning and dose delivery. The audit is implemented at the national level with IAEA assistance. The national counterparts conduct the TPS audit at local radiotherapy centres through on-site visits. TPS calculated doses are compar...
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References19
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#1Andrea Molineu (University of Texas MD Anderson Cancer Center)H-Index: 17
#2N. Hernandez (University of Texas MD Anderson Cancer Center)H-Index: 4
Last. David S Followill (University of Texas MD Anderson Cancer Center)H-Index: 46
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#1Eduardo Rosenblatt (IAEA: International Atomic Energy Agency)H-Index: 18
#2Joanna Izewska (IAEA: International Atomic Energy Agency)H-Index: 18
Last. Philippe AutierH-Index: 70
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Summary Radiotherapy is used for cure or palliation in around half of patients with cancer. We analysed data on radiotherapy equipment in 33 European countries registered in the Directory of Radiotherapy Centres (DIRAC) database, managed by the International Atomic Energy Agency. As of July, 2012, Europe had 1286 active radiotherapy centres. The average number of teletherapy machines per radiotherapy centre ranged from 1·2 to 7·0 in different countries. Nordic countries, the UK, the Netherlands,...
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#1L. RutonjskiH-Index: 2
#2B. PetrovicH-Index: 6
Last. Joanna Izewska (IAEA: International Atomic Energy Agency)H-Index: 18
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Background Independent external audits play an important role in quality assurance programme in radiation oncology. The audit supported by the IAEA in Serbia was designed to review the whole chain of activities in 3D conformal radiotherapy (3D-CRT) workflow, from patient data acquisition to treatment planning and dose delivery. The audit was based on the IAEA recommendations and focused on dosimetry part of the treatment planning and delivery processes.
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#1David S Followill (University of Texas MD Anderson Cancer Center)H-Index: 46
#2Stephen F Kry (University of Texas MD Anderson Cancer Center)H-Index: 41
Last. Geoffrey S. Ibbott (University of Texas MD Anderson Cancer Center)H-Index: 47
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#1Jessica Lowenstein (University of Texas MD Anderson Cancer Center)H-Index: 10
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Last. David S FollowillH-Index: 46
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#1Antony L PalmerH-Index: 14
#2Bongile MzendaH-Index: 4
Last. R WillsH-Index: 1
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#2Rainer SchmidtH-Index: 12
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Abstract Background and purpose The methodology developed by IAEA for dosimetric quality control of treatment planning systems has been tested in different hospitals through a pilot study. The aim was to verify the methodology and observe the range of deviations between planned and delivered doses in 3D conformal radiotherapy in situations close to a clinical setting. Material and methods The methodology was based on an anthropomorphic phantom representing the human thorax, and simulates the who...
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#1Morten Pettersen (Rikshospitalet–Radiumhospitalet)H-Index: 8
#2Edwin Aird (Mount Vernon Hospital)H-Index: 22
Last. Dag Rune Olsen (University of Oslo)H-Index: 34
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Abstract Background and purpose The aim of this study was to investigate the impact of appropriate dosimetry quality assurance (QA) on patient number required in radiotherapy randomized control trials (RCT). Materials and methods The steepness of clinical dose–response curves, γ clin. , was calculated by a convoluting a biological dose–response distribution and the distribution of technical and dosimetrical factors. Population size calculation was performed taking into account γ clin. and expect...
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#2Nuria JornetH-Index: 16
Last. Maria RibasH-Index: 24
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To evaluate the dose values predicted by several calculation algorithms in two treatment planning systems, Monte Carlo (MC) simulations and measurements by means of various detectors were performed in heterogeneous layer phantoms with water- and bone-equivalent materials. Percentage depth doses (PDDs) were measured with thermoluminescent dosimeters (TLDs), metal-oxide semiconductor field-effect transistors (MOSFETs), plane parallel and cylindrical ionization chambers, and beam profiles with film...
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#2Victor HernandezH-Index: 12
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