Estrogen receptor β inhibits 17β-estradiol-stimulated proliferation of the breast cancer cell line T47D
Volume: 101, Issue: 6, Pages: 1566 - 1571
Published: Jan 26, 2004
Abstract
Estrogen receptor (ER) beta counteracts the activity of ERalpha in many systems. In agreement with this, we show in this study that induced expression of ERbeta in the breast cancer cell line T47D reduces 17beta-estradiol-stimulated proliferation when expression of ERbeta mRNA equals that of ERalpha. Induction of ERbeta reduces growth of exponentially proliferating cells with a concomitant decrease in components of the cell cycle associated with...
Paper Details
Title
Estrogen receptor β inhibits 17β-estradiol-stimulated proliferation of the breast cancer cell line T47D
Published Date
Jan 26, 2004
Volume
101
Issue
6
Pages
1566 - 1571
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