Genetic variants are major determinants of CSF antibody levels in multiple sclerosis
Abstract
Immunological hallmarks of multiple sclerosis include the production of antibodies in the central nervous system, expressed as presence of oligoclonal bands and/or an increased immunoglobulin G index—the level of immunoglobulin G in the cerebrospinal fluid compared to serum. However, the underlying differences between oligoclonal band-positive and -negative patients with multiple sclerosis and reasons for variability in immunoglobulin G index...
Paper Details
Title
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis
Published Date
Jan 22, 2015
Journal
Volume
138
Issue
3
Pages
632 - 643
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