Intracortical Myelin Links with Performance Variability across the Human Lifespan: Results from T1- and T2-Weighted MRI Myelin Mapping and Diffusion Tensor Imaging

Cerebral myelin maturation and aging-related degradation constitute fundamental features of human brain integrity and functioning. Although mostly studied in the white matter, the cerebral cortex contains significant amounts of myelinated axons. However, how intracortical myelin content evolves during development, decays in aging, and links with cognition remain poorly understood. Several studies have shown the potential of mapping myelin in the...