Clarithromycin Inhibits Interleukin-13–Induced Goblet Cell Hyperplasia in Human Airway Cells
Volume: 45, Issue: 5, Pages: 1075 - 1083
Published: Nov 1, 2011
Abstract
IL-13 is a T-helper class 2 cytokine that induces goblet cell hyperplasia and mucus production in airway epithelial cells. Because macrolide antibiotics are known to have immunomodulatory and mucoregulatory properties, the aim of this study was to examine the effect of clarithromycin on IL-13-induced goblet cell hyperplasia and mucin hypersecretion in normal human bronchial epithelial (NHBE) cells. NHBE cells were cultured to differentiation at...
Paper Details
Title
Clarithromycin Inhibits Interleukin-13–Induced Goblet Cell Hyperplasia in Human Airway Cells
Published Date
Nov 1, 2011
Volume
45
Issue
5
Pages
1075 - 1083
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