Dose-response Relationship for Life-shortening and Carcinogenesis in Mice Irradiated at Day 7 Postnatal Age with Dose Range below 1 Gy of Gamma Rays

This study was designed to elucidate the dose-response relationships for life-shortening and tumorigenic effect in the dose range below 1 Gy of gamma rays delivered during the infant period. Female B6C3F1 mice were irradiated with 0.10, 0.48 or 0.95 Gy at 7 days of age. All irradiated mice were allowed to live out their entire life span together with a simultaneously ongoing control group under a specific pathogen-free condition. Shortening of...