Antibody–Drug Conjugates: An Emerging Concept in Cancer Therapy
Volume: 53, Issue: 15, Pages: 3796 - 3827
Published: Feb 20, 2014
Abstract
Traditional cancer chemotherapy is often accompanied by systemic toxicity to the patient. Monoclonal antibodies against antigens on cancer cells offer an alternative tumor‐selective treatment approach. However, most monoclonal antibodies are not sufficiently potent to be therapeutically active on their own. Antibody–drug conjugates (ADCs) use antibodies to deliver a potent cytotoxic compound selectively to tumor cells, thus improving the...
Paper Details
Title
Antibody–Drug Conjugates: An Emerging Concept in Cancer Therapy
Published Date
Feb 20, 2014
Volume
53
Issue
15
Pages
3796 - 3827
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