Ion Channels in Innate and Adaptive Immunity
Abstract
Ion channels and transporters mediate the transport of charged ions across hydrophobic lipid membranes. In immune cells, divalent cations such as calcium, magnesium, and zinc have important roles as second messengers to regulate intracellular signaling pathways. By contrast, monovalent cations such as sodium and potassium mainly regulate the membrane potential, which indirectly controls the influx of calcium and immune cell signaling. Studies...
Paper Details
Title
Ion Channels in Innate and Adaptive Immunity
Published Date
Mar 21, 2015
Journal
Volume
33
Issue
1
Pages
291 - 353
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