Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection

Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung tissue. Although pathological effects of SM have been widely considered, molecular and cellular mechanisms for these pathologies are not well understood, yet. General cellular and molecular events such as inflammation, DNA damage, cell membrane disintegrity, apoptosis and cell death were observed either in in vitro or in vivo models exposed to SM....