Potential use of TNF-α inhibitors in systemic sclerosis
Abstract
Systemic sclerosis (SSc) is a rare connective tissue disease characterized by chronic inflammation and fibrosis of the skin, vascular abnormalities and variable involvement of organs. TNF-α has a central role in initial host response to infections and in the pathogenesis of various systemic immune-mediated diseases. Serum levels of TNF-α are elevated in patients with SSc and favor the development of pulmonary fibrosis and pulmonary arterial...
Paper Details
Title
Potential use of TNF-α inhibitors in systemic sclerosis
Published Date
Mar 1, 2014
Journal
Volume
6
Issue
3
Pages
283 - 289
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Notes
History