Noise robust spatially regularized myelin water fraction mapping with the intrinsic B₁-error correction based on the linearized version of the extended phase graph model

Purpose To improve the quantification accuracy of transverse relaxometry by accounting for B1-error, after minimizing slice profile imperfections. Materials and Methods The slice profile of refocusing pulses was optimized by setting refocusing slice thicknesses three times that of the excitation pulse. The first step of data processing combined the L-curve approach with the linearized version of the extended phase graph model to jointly estimate...