Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis

Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence for treatment of the condition with antidepressants and psychological therapies is conflicting.Systematic review and meta-analysis of randomised controlled trials (RCTs). MEDLINE, EMBASE and the Cochrane Controlled Trials Register were searched (up to May 2008).RCTs based in primary, secondary and tertiary care.Adults with IBS.Antidepressants versus...