Time course of lewisite-induced skin lesions and inflammatory response in the SKH-1 hairless mouse model
Abstract
Data on the toxicity of lewisite ( L ), a vesicant chemical warfare agent, are scarce and conflicting, and the use of the specific antidote is not without drawbacks. This study was designed to evaluate if the SKH ‐1 hairless mouse model was suitable to study the L ‐induced skin injuries. We studied the progression of lesions following exposure to L vapors for 21 days using paraclinical parameters (color, transepidermal water loss ( TEWL ), and...
Paper Details
Title
Time course of lewisite-induced skin lesions and inflammatory response in the SKH-1 hairless mouse model
Published Date
Mar 1, 2014
Volume
22
Issue
2
Pages
272 - 280
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