Combining MRI With PET for Partial Volume Correction Improves Image-Derived Input Functions in Mice

Volume: 62, Issue: 3, Pages: 628 - 633
Published: Jun 1, 2015
Abstract
Accurate kinetic modelling using dynamic PET requires knowledge of the tracer concentration in plasma, known as the arterial input function (AIF). AIFs are usually determined by invasive blood sampling, but this is prohibitive in murine studies due to low total blood volumes. As a result of the low spatial resolution of PET, image-derived input functions (IDIFs) must be extracted from left ventricular blood pool (LVBP) ROIs of the mouse heart....
Paper Details
Title
Combining MRI With PET for Partial Volume Correction Improves Image-Derived Input Functions in Mice
Published Date
Jun 1, 2015
Volume
62
Issue
3
Pages
628 - 633
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