The Impacts of Serum Uric Acid on arterial hemodynamics and Cardiovascular Risks.

Hyperuricemia, and its clinical manifestation gout, is a metabolic disease process that has been recognized since the dawn of medical inquiry. Uric acid was hypothesized to be a mediator of cardiovascular disease for period of time. Epidemiological correlations of hyperuricemia with hypertension and cardiovascular events were evident for two centuries' studies. With recent animal studies shedding light on the causal mechanisms of hypertension,...