Endoscopic Ultrasound with Fine Needle Aspiration (EUS-FNA) with Pancreatic Cyst Fluid DNA Analysis Influences Clinical Management in Patients with Cystic Lesions of the Pancreas

Differentiation of malignant from benign cystic lesions of the pancreas is difficult and recent studies confirm as many as 78% of patients (pts) will undergo unnecessary resection for benign lesions. This prospective study evaluated the utility of a novel, DNA mutational analysis panel (PathFinderTG™) to influence management of pancreatic cystic lesions. Methods: 35 pts (40% M, mean age 61 yrs [32-88]) who underwent EUS-FNA of pancreatic cystic...