Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases.

Volume: 8, Issue: 9, Pages: 1227 - 1236
Published: Oct 24, 2012
Abstract
Interleukin (IL)-6, a cytokine featuring redundancy and pleiotropic activity, contributes to host defense against acute environmental stress, while dysregulated persistent IL-6 production has been demonstrated to play a pathological role in various autoimmune and chronic inflammatory diseases. Targeting IL-6 is thus a rational approach to the treatment of these diseases. Indeed, clinical trials of tocilizumab, a humanized anti-IL-6 receptor...
Paper Details
Title
Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases.
Published Date
Oct 24, 2012
Volume
8
Issue
9
Pages
1227 - 1236
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