Na+ channel expression along axons in multiple sclerosis and its models.
Volume: 25, Issue: 11, Pages: 584 - 591
Published: Nov 1, 2004
Abstract
Following the loss of myelin from axons in multiple sclerosis, some axons recover the ability to conduct impulses despite the absence of an insulating sheath, providing a basis for remission of clinical deficits. By contrast, other axons degenerate and contribute to non-remitting clinical deficits and, thus, disability. Investigations using laboratory models of multiple sclerosis indicate that altered expression of two distinct isoforms of Na+...
Paper Details
Title
Na+ channel expression along axons in multiple sclerosis and its models.
Published Date
Nov 1, 2004
Volume
25
Issue
11
Pages
584 - 591
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