Statin therapy in patients with cirrhosis
Abstract
Cardiovascular disease is one of the leading causes of death among patients with cirrhosis and following liver transplantation. Although 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors ('statins') reduce the risk of cardiovascular events, fears about hepatotoxicity have historically led to underuse in patients with liver disease. In addition, the pharmacokinetics of statins can be significantly altered in cirrhosis, creating challenges with...
Paper Details
Title
Statin therapy in patients with cirrhosis
Published Date
Aug 8, 2014
Journal
Volume
6
Issue
4
Pages
255 - 261
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