Antiplatelet Effect of Aspirin in Patients With Cerebrovascular Disease

Background and Purpose— Aspirin is used commonly to prevent ischemic strokes and other vascular events. Although aspirin is considered safe and effective, it has limited efficacy with a relative risk reduction of 20% to 25% for ischemic stroke. We sought to determine if aspirin as currently used is having its desired antiplatelet effects. Methods— We ascertained patients with cerebrovascular disease who were taking only aspirin as an...