Impact of MDM2 Single Nucleotide Polymorphism on Oral Squamous Cell Carcinoma Risk

Volume: 71, Issue: 2, Pages: 993 - 998
Published: Oct 17, 2014
Abstract
Mouse Double Minute 2 (MDM2) has emerged as a pivotal cellular antagonist of p53 by destructing the suppressive function of p53 against tumorigenesis. The MDM2 309 T > G polymorphism has been studied for its association with oral squamous cell carcinoma (OSCC) susceptibility, but the evidence was confusing and inconclusive. Here, we performed a meta-analysis to estimate the effects of the 309 T > G polymorphism on the development of OSCC. The...
Paper Details
Title
Impact of MDM2 Single Nucleotide Polymorphism on Oral Squamous Cell Carcinoma Risk
Published Date
Oct 17, 2014
Volume
71
Issue
2
Pages
993 - 998
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