Evidence-based sample size calculations based upon updated meta-analysis.
Abstract
Meta-analyses of randomized controlled trials (RCTs) provide the highest level of evidence regarding the effectiveness of interventions and as such underpin much of evidence-based medicine. Despite this, meta-analyses are usually produced as observational by-products of the existing literature, with no formal consideration of future meta-analyses when individual trials are being designed. Basing the sample size of a new trial on the results of...
Paper Details
Title
Evidence-based sample size calculations based upon updated meta-analysis.
Published Date
May 30, 2007
Journal
Volume
26
Issue
12
Pages
2479 - 2500
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