Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs
Volume: 289, Issue: 1, Pages: L67 - L74
Published: Jul 1, 2005
Abstract
Respiratory tract lesions induced by the chemical warfare agent sulfur mustard (SM) are characterized by epithelial damages associated with inflammatory cell infiltration. Here we evaluated the imbalance between gelatinase and tissue inhibitors of metalloproteinases (TIMPs), and we tested pretreatment with the protease inhibitor doxycycline. Guinea pigs were intoxicated intratracheally with SM and evaluated 24 h after exposure. Matrix...
Paper Details
Title
Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs
Published Date
Jul 1, 2005
Volume
289
Issue
1
Pages
L67 - L74
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