Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients With Pancreatic Cancer
Abstract
We investigated the prevalence of germline mutations in APC, ATM, BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, and TP53 in patients with pancreatic cancer.The Ontario Pancreas Cancer Study enrolls consenting participants with pancreatic cancer from a province-wide electronic pathology database; 708 probands were enrolled from April 2003 through August 2012. To improve the precision of BRCA2 prevalence estimates, 290...
Paper Details
Title
Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients With Pancreatic Cancer
Published Date
Mar 1, 2015
Journal
Volume
148
Issue
3
Pages
556 - 564
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