Synergism Between Anticholinergic and Oxime Treatments Against Sarin-Induced Ocular Insult in Rats

Volume: 146, Issue: 2, Pages: 301 - 310
Published: May 7, 2015
Abstract
Eye exposure to the extremely toxic organophosphorus sarin results in long-term miosis and visual impairment. As current treatment using atropine or homatropine eye drops may lead to considerable visual side effects, alternative combined treatments of intramuscular (im) oximes (16.8 µmol/kg, im) with atropine (0.5 mg/kg, im) or with the short acting antimuscarinic tropicamide (0.5%; w/v) eye drops were thus evaluated. The combined treatments...
Paper Details
Title
Synergism Between Anticholinergic and Oxime Treatments Against Sarin-Induced Ocular Insult in Rats
Published Date
May 7, 2015
Volume
146
Issue
2
Pages
301 - 310
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