Abstract Six new aromadendrin-derived flavanoids have been isolated from Hypnum cupressiforme; hypnogenol A; hypnogenol B; 3,5,7,4′,3″,5″,7″,3″′4″−nonahydroxy-3′-6″-biflavanone, 3,5,7,4′,3″,5″,7″-heptahydroxy-3′-O-4″ -biflavanone; 1″′,2″′,3″′,4″′-tetrahydro-3,3″,5,5″,7,7″-hexahydroxy-4″′-keto-3′-1″′,4′-O-2″′-biflavanone and 3,5,7, 4′-tetrahydroxy-3′-(3″-formyl-6″-hydroxyphenyl)-flavanone.
From Scutellaria alpina L., two new flavones (I and II) were isolated, together with eighteen known flavonoids. The structures of I and II were shown to be 5, 2', 6'-trihydroxy-6, 7, 8-trimethoxyflavone and 5, 5", 6, 6", 7, 7"-hexahydroxy-8, 8"-biflavone(8, 8"-bibaicalein) on the basis of the chemical and spectral data. Compound I has already been synthesized.
Abstract The novel macrocyclic biflavonoid bartramiaflavone, which consists of two equilibrating cyclo-oxo tautomers has been isolated from Bartramia pomiformis. It is easily dehydrated to anhydro-bartramiaflavone, a doubly linked biluteolin. The structures of the compounds were elucidated spectroscopically.
Abstract The flavonoids of five Chrozophora species were investigated and found to be the glycosides of kaempferol, quercetin, apigenin, luteolin and acacetin. An acylated glycoside of apigenin was also isolated, as well as smaller amounts of the biflavone amentoflavone.
From Rhytidiadelphus squarrosus the hitherto unknown biflavone 5′-hydroxyrobustaflavone and the three known biflavonoids 5′-hydroxyamentoflavone,5′,3′′′-dihydroxyamentoflavone and 2,3-dihydro-5′-hydroxyamentoflavone have been isolated.
Abstract Flavonoids common to both Libocedrus bidwillii and L. plumosa , which were sampled throughout New Zealand, are: kaempferol and quercetin 3-rhamnoside, kaempferol and quercetin 3-rhamnoside-7-glucoside, quercetin 3-glucoside, apigenin and luteolin 7-glucoside, luteolin 7-di- (and tri)-glucosides, amentoflavone, 7- O -methylamentoflavone, 2,3-dihydroamentoflavone, and the new flavonoids, 8-hydroxyapigenin and 8-hydroxyluteolin 7- O -xylosides and 7- O -methyl-2,3-dihydroamentoflavone. Lib...
Abstract Natural biflavonoids, such as amentoflavone, bilobetin, ginkgetin, isoginkgetin, taiwaniaflavone, morelloflavone, delicaflavone, hinokiflavone, and other derivatives (~40 biflavonoids), are isolated from Selaginella sp., Ginkgo biloba, Garcinia sp., and several other species of plants. They are able to exert therapeutic benefits by regulating several proteins/enzymes (PPAR-γ, CCAAT/enhancer-binding protein α [C/EBPα], STAT5, pancreatic lipase, PTP1B, fatty acid synthase, α-glucosidase [...