The Proinflammatory Cytokine TNF-α -308 AA Genotype is Associated with Polyglandular Autoimmunity

Volume: 38, Issue: 3-4, Pages: 255 - 267
Published: Jan 1, 2009
Abstract
Data regarding polymorphisms of immunoregulatory genes in polyglandular autoimmunity (PGA) are lacking. We have analyzed whether the polymorphism of the proinflammatory cytokine gene TNF-alpha; -308 and mutations of the autoimmune regulator (AIRE) gene were associated with PGA in adults. Sixty-seven patients with PGA and 209 healthy controls were genotyped by multiplex minisequencing with capillary electrophoresis on an ABI PRISM-310 genetic...
Paper Details
Title
The Proinflammatory Cytokine TNF-α -308 AA Genotype is Associated with Polyglandular Autoimmunity
Published Date
Jan 1, 2009
Volume
38
Issue
3-4
Pages
255 - 267
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