Kinetic Modeling of the Serotonin 5-HT1B Receptor Radioligand [11C]P943 in Humans

Volume: 30, Issue: 1, Pages: 196 - 210
Published: Sep 23, 2009
Abstract
[ 11 C]P943 is a new radioligand recently developed to image and quantify serotonin 5-Hydroxytryptamine (5-HT 1B ) receptors with positron emission tomography (PET). The purpose of this study was to evaluate [ 11 C]P943 for this application in humans, and to determine the most suitable quantification method. Positron emission tomography data and arterial input function measurements were acquired in a cohort of 32 human subjects. Using arterial...
Paper Details
Title
Kinetic Modeling of the Serotonin 5-HT1B Receptor Radioligand [11C]P943 in Humans
Published Date
Sep 23, 2009
Volume
30
Issue
1
Pages
196 - 210
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