Analysis of arginine and methylated metabolites in human plasma by field amplified sample injection capillary electrophoresis tandem mass spectrometry
Abstract
A CE ion trap tandem MS method was optimised for the analysis of arginine, monomethyl‐ and (symmetric and asymmetric) dimethylarginines in human plasma after a very reduced sample pretreatment step involving a simple protein precipitation with ACN. Several parameters affecting the analytes MS ionization and the capillary electrophoretic separation were carefully studied and optimised. The complete separation of arginine, monomethylarginine and...
Paper Details
Title
Analysis of arginine and methylated metabolites in human plasma by field amplified sample injection capillary electrophoresis tandem mass spectrometry
Published Date
May 26, 2010
Journal
Volume
31
Issue
11
Pages
1894 - 1902
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