Dietary Soybean Protein Prevents Bone Loss in an Ovariectomized Rat Model of Osteoporosis

The purpose of this study was to examine whether soybean protein isolate prevents bone loss induced by ovarian hormone deficiency. Thirty-two 95-d-old Sprague-Dawley rats were randomly assigned to four treatment groups [sham-operated (sham); ovariectomized (ovx); ovx + soybean; ovx + 17β-estradiol (E2)] and killed after 30 d. Rats in the sham, ovx and ovx + 17β-estradiol groups were fed a casein-based diet, and the soybean group was fed soybean...