Human inversions and their functional consequences
Abstract
Polymorphic inversions are a type of structural variants that are difficult to analyze owing to their balanced nature and the location of breakpoints within complex repeated regions. So far, only a handful of inversions have been studied in detail in humans and current knowledge about their possible functional effects is still limited. However, inversions have been related to phenotypic changes and adaptation in multiple species. In this review,...
Paper Details
Title
Human inversions and their functional consequences
Published Date
May 20, 2015
Volume
14
Issue
5
Pages
369 - 379
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