Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes
Abstract
Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) function and receptor cross-talk with other nuclear receptors, including PPARγ and retinoic acid receptors (RARs), was examined using stable human HaCaT keratinocyte cell lines over-expressing PPARβ/δ or PPARγ. Enhanced ligand-induced expression of two known PPAR target genes, adipocyte differentiation-related protein (ADRP) and angiopoietin-like protein 4 (ANGPTL4), was found in HaCaT...
Paper Details
Title
Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes
Published Date
Dec 1, 2011
Journal
Volume
23
Issue
12
Pages
2039 - 2050
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