Quantitation of Biomarkers of Exposure to Nitrogen Mustards in Urine from Rats Dosed with Nitrogen Mustards and from an Unexposed Human Population

Volume: 28, Issue: 5, Pages: 320 - 326
Published: Jul 1, 2004
Abstract
The nitrogen mustards bis(2-chloroethyl)ethylamine (HN1), bis(2-chloroethyl)methylamine (HN2), and tris(2-chloroethyl)amine (HN3) have the potential to be used as chemical terrorism agents because of their extreme vesicant properties. We modified a previously reported method to incorporate automated solid-phase extraction, improve chromatography, and include the urinary metabolite for HN3. The improved method was used to measure levels of the...
Paper Details
Title
Quantitation of Biomarkers of Exposure to Nitrogen Mustards in Urine from Rats Dosed with Nitrogen Mustards and from an Unexposed Human Population
Published Date
Jul 1, 2004
Volume
28
Issue
5
Pages
320 - 326
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