TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
Abstract
▪ Abstract As targets for the immunosuppressive drugs cyclosporin A and FK506, transcription factors of the NFAT (nuclear factor of activated T cells) family have been the focus of much attention. NFAT proteins, which are expressed in most immune-system cells, play a pivotal role in the transcription of cytokine genes and other genes critical for the immune response. The activity of NFAT proteins is tightly regulated by the...
Paper Details
Title
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
Published Date
Apr 1, 1997
Journal
Volume
15
Issue
1
Pages
707 - 747
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History