How Do Liquid-Based Preparations of Thyroid Fine-Needle Aspiration Compare with Conventional Smears? An Analysis of 5475 Specimens

Fine-needle aspiration (FNA) plays a pivotal role in the initial evaluation of patients with thyroid nodules. Traditionally, aspirated material is expelled directly onto the microscope slide to make a conventional smear (CS). Recently, liquid-based preparations (LBP) have gained in popularity. This study compares the accuracy of these two preparation techniques in diagnosing thyroid nodules.A clinical database containing 5475 thyroid cytology...