Notch Signaling Pathway as a Therapeutic Target in Breast Cancer
Abstract
The highly conserved Notch signaling pathway is involved in regulating a number of key cellular processes. This pathway has been implicated in both the development and progression of breast cancer and has emerged as a possible therapeutic target. Several clinical trials are currently underway to determine if targeting the Notch pathway with drugs such as the γ-secretase inhibitors may be an effective therapeutic strategy that improves outcomes...
Paper Details
Title
Notch Signaling Pathway as a Therapeutic Target in Breast Cancer
Published Date
Jan 1, 2011
Volume
10
Issue
1
Pages
9 - 15
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