Metalloproteinases and Metalloproteinase Inhibitors in Age-Related Diseases
Abstract
Degradation of the extracellular matrix is an important feature of embryonic development, morphogenesis, angiogenesis, tissue repair and remodeling. It is precisely regulated under physiological conditions, but when dysregulated it becomes a cause of many diseases, including atherosclerosis, osteoarthritis, diabetic vascular complications, and neurodegeneration. Various types of proteinases are implicated in extracellular matrix degradation, but...
Paper Details
Title
Metalloproteinases and Metalloproteinase Inhibitors in Age-Related Diseases
Published Date
May 31, 2014
Volume
20
Issue
18
Pages
2993 - 3018
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Notes
History